Electroanalytical Investigation and Simultaneous Determination of Etodolac and Thiocolchicoside at a Non-Modified Glassy Carbon Electrode in Anionic Surfactant Media

In this study, a differential pulse voltammetry method was designed for the simultaneous determination of etodolac and thiocolchicoside in a tablet dosage form. This method is a sensitive, costless and reproducible one initially designed for the simultaneous determination of etodolac and thiocolchicoside using bare/unmodified glassy carbon electrode in the presence of sodium dodecyl sulfate. At optimized conditions, the method showed linear responses with etodolac and thiocolchicoside concentration in the range of 1 mu M to 80 mu M. The limits of detection and quantification were calculated as 0.11 mu M and 0.38 mu M for etodolac and 0.20 mu M and 0.67 mu M for thiocolchicoside, respectively.