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Mersin Üniversitesi Sağlık Bilimleri Dergisi4
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Journal of Anatolian Environmental and Animal Sciences3
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Mediterranean Fisheries and Aquaculture Research (MedFAR)3
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ANASAY DERGİSİ2
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Advanced Underwater Sciences2
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EKSEN Dokuz Eylül Üniversitesi Mimarlık Fakültesi Dergisi2
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Journal of Tourism and Gastronomy Studies2
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KORKUT ATA TÜRKİYAT ARAŞTIRMALARI DERGİSİ2
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Natural and Engineering Sciences2
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Niğde Ömer Halisdemir Üniversitesi Mühendislik Bilimleri Dergisi2
SERÜVENİ KAPSAMINDA IŞIK VE GÖLGEYE DAİR GÜNÜMÜZ SANATINDA ÖZNELLEŞMİŞ NESNELER VE ÖTESİ
Doç. Can KÜÇÜKTEPEPINAR
SERÜVENİ KAPSAMINDA IŞIK VE GÖLGEYE DAİR GÜNÜMÜZ SANATINDA ÖZNELLEŞMİŞ NESNELER VE ÖTESİ Can KÜÇÜKTEPEPINAR Doç. Can KÜÇÜKTEPEPINAR, Mersin Üniversitesi cank@mersin.edu.tr G.S.F Heykel Bölümü Öğretim Üyesi Küçüktepepınar, Can. “Serüveni Kapsamında Işık ve Gölgeye Dair Günümüz Sanatında Öznelleşmiş Nesneler ve Ötesi”. idil, 108 (2023 Ağustos): s. 1123–1138. doi: 10.7816/idil-12-108-06 ÖZ Işığın yayılım, yansıma ve kırılması tarihsel boyutu ile insanlık serüveni içerisinde bilimsel- sanatsal teorik ve pratik bir biçimde irdelenmiştir. Özne insanın/sanatçının duyulur algılar yoluyla yaşamsal deneyimlerinin içsel ve düşünsel gerçeklikleri ve bunun sonucu ışık ve gölgeye dair oluşturulmuş, öncü sanatsal yapıtlar, yirminci yüzyıldan günümüz dünyasına kadar, iç ve dış mekân ...
Enhancement of taxane production in cell suspension culture of Corylus avellana L. Kalınkara by elicitation and precursor feeding
Doğan, Ahmet
Paclitaxel (trademark Taxol®) is the most effective chemotherapeutic agent against a wide range of cancers. Hazelnut (Corylus avellana L.) cell culture is a promising and inexpensive strategy for producing paclitaxel and related taxanes. This study evaluated the effect of elicitation and taxane precursor feeding for the enhancement of taxanes in a Turkish hazelnut (C. avellana cv. ‘Kalınkara’) cell suspension culture. Elicitor methyl jasmonate (100, 200 and 300 µmol L−1) and precursor phenylalanine (3μmol, 3 and 6 mmol L−1) were tested in cell suspension cultures. While methyl jasmonate increased the accumulation of taxanes, especially cephalomannine, via induction of the paclitaxel biosynthetic pathway, phenylalanine slightly induced the conversion of 10-deacetylbaccatin III and baccatin ...
Türk Fındık Çeşitlerinde Antikanser Taksanların Biyoteknolojik Üretimi için Optimize Edilmiş Model Hücre Kültür Sistemi
Doğan, Ahmet
Paklitaksel çeşitli kanser hastalıklarının tedavisinde yaygın olarak kullanılan bir diterpenoiddir. Fındık (Corylus avellana L.) hücre süspansiyon kültürleri, paklitakselin (PTX) yanı sıra, çeşitli kanserlerde etkinliği yakın zamanda gösterilen sefalomannin (CEPH) ve bu taksanların yarı sentezinde kullanılan öncüller olan 10-deasetil bakkatin III (10DAB) ve bakkatin III (BACIII) gibi önemli taksanların üretimi için uygun sistemlerdir. Biyoteknolojik yolla taksan üretimi için antikanser sekonder metabolitlerin üretiminin artırılması gerekmektedir. Türk fındık çeşitlerinden Kalınkara hücre süspansiyon kültürlerinde biyokütlenin ve hücre dışına salgılanan taksanların üretiminin artırılması için elisitasyon koşulları ilk kez belirlenmiştir.
Determination of the effect of silica nanoparticles on TRP currents in retinal pigment epithelial cells by entropy measurement
Söğüt, Fatma | Kibar, Deniz | Yılmaz, Şakir Necat | Çömelekoğlu, Ülkü
Ion channels in cell membranes are gated, water-filled pores that allow passive transport of ions across the membrane along their electrochemical gradient. Recent studies have shown that nanoparticles can interact with ion channels and change their currents kinetics properties of the channel. In this study, we used the transient receptor potential (TRP) channel currents in retinal pigment epithelial (RPE) cells recorded by whole-cell patch clamp technique to observe the silica nanoparticle-ion channel interaction. For whole cell recordings, we clamped membrane potential to −40 mV and used a ramp of 1000 ms duration for stimulation. The ramp was increased from −140 mV to +60 mV. We used windowed scalogram entropy and compared the results with windowed scale index method. Our results indicat...
Study and development of electrospun (TPU, PA-6) / silicone bilayer membranes for congenital diaphragmatic hernia repair
Bölgen, Nimet | Yılmaz, Şakir Necat | Kibar, Deniz
Large defects in the congenital diaphragmatic hernia (CDH) are treated by prosthetic materials, most frequently polytetrafluoroethylene (PTFE), with high complications. The purpose of this study is to develop a novel electrospun double-faced prosthesis that will minimize these surgical complications. Polyamide 6 (PA-6) and thermoplastic polyurethane (TPU) nanofibers were prepared by solution electrospinning, and room temperature vulcanized silicone (RTV) was used in electrospinning by dip-coating to develop a double-faced membrane. The results demonstrate that the duration of electrospinning and thickness of silicone layers influence the morphology of the bilayer scaffolds. Electrospun bilayer polyamide 6/silicone and thermoplastic polyurethane/silicone scaffolds are fabricated as potentia...
The Roots of the Soviet-Syrian Alliance: A Neo-Gramscian Perspective
Akgüden, Muhterem & Atmaca, Ayşe Ömür
The Soviet and Baath regimes enjoyed a consensual relationship between the 1940s and the 1980s. The nature of this relationship was shaped both by the need for an alliance in a period of Cold War bipolarity and by shared common ideological worldviews such as anti-imperialism and socialism. These relations were not free from pragmatism to a certain extent, as the degree of commitment to socialism and Pan-Arabism within the Baath Party sometimes fluctuated. Nevertheless, the generally close relationship between Syria and the USSR cannot be seen as a purely pragmatic strategy; rather, this relationship's ideational, institutional, and material dimensions must be considered as a whole. In this context, this article examines Soviet-Syrian relations from the perspective of neo-Gramscian heg...
Artificial Intelligence in Digital Public Relations: A Delphi Study
Çataldaş, ibrahim
Digitalization has brought many new technologies. One of these technologies is artificial intelligence, which has started a new change process in public relations. Some digital public relations duties are currently being performed using artificial intelligence, but it is still unclear what role this technology will play in the field's future. In this study, artificial intelligence is discussed in the context of digital public relations. In this vein, the primary purpose of this study is to identify new technologies and trends that may affect the future transformation of public relations. According to the purpose of the study, expert opinions were used by applying the Delphi technique in the research part. The goal of the first round of this research, which consists of two rounds, was ...
The Usage of New Media in Language Learning: The Turkish Learning Journey of The Russian Children Living in Mersin
Doğan Topçu, Aslıhan | Erdönmez, Soner | Budak, Goncagül
The Usage of New Media in Language Learning: The Turkish Learning Journey of The Russian Children Living in Mersin
ULUSLARARASI HALKLA İLİŞKİLER BAĞLAMINDA KAMU DİPLOMASİSİ: 2022 FIFA DÜNYA KUPASI ÜZERİNE BİR İNCELEME
Çataldaş, İbrahim
Kurum ve işletmelerin hedef kitlelerine yönelik olarak yürüttüğü iletişim çalışmalarını kapsayan halkla ilişkiler, dünyadaki küresel gelişmelere bağlı olarak günümüzde daha geniş bir uygulama alanı bulmaktadır. Bu nedenle günümüzde uluslararası halkla ilişkiler ve kamu diplomasisi faaliyetleri, yabancı kamuoyu ile iletişim kurmak, ülkeyi tanıtmak, imaj, itibar ve tutumda olumlu bir değişiklik elde etmek gibi amaçlarla ön plana çıkmaktadır. Bu amaçlara yönelik olarak uluslararası spor organizasyonlarının, kamu diplomasisi ve uluslararası halkla ilişkiler faaliyetleri açısından oldukça önemli bir rol oynadığını söylemek mümkündür. Farklı dönemlerde farklı ülkelerin ev sahipliğini yaptığı uluslararası spor etkinlikleri, her yıl dünyanın farklı yerlerinden ziyaretçiler çekmektedir. Bu nedenle ...
Turist Rehberlerinin Yorumlama Performansının Hatırlanır Tur Deneyimleri ve Davranışsal Niyetler Üzerindeki Etkisi
Atçı, Dilek
Although considerable research has been conducted on interpretation in tourism and tour guiding services, it has mainly focused on evaluating the interpretation or outcomes of it. This study was designed to examine tour guides' interpretation performance, focusing on interpretation techniques within the frame of the EROT theoretical model. In this framework, the aim is to test the effect of the interpretation performance of tour guides on memorable tour experiences and behavioural intentions. The data were collected from 227 tourists participating in guided heritage tours in Turkey. The empirical findings proposed the theory within the tour-guiding context of two dimensions as organized and relevant interpretation. Structural equation modelling showed that organized interpretation per...
Organizational Performance Evaluation of Flour Manufacturers: A Case Study of Hıdıroğlu Flour Mills
HIDIROĞLU, DUYGU
This study aims to examine how flour producers implement Organizational Theory Principles to their process and to define which organizational environmental and structural factors, culture and systems are appropriate for flour companies in order to improve companies’ success and entreprenuerial skills. For this purpose, this study analyzes a flour company and provides implications of the findings and limitations for the organization, its members, environment and stakeholders. In this study, while examining on flour companies, a clear hierarchy in the organizations is observed in general. The flour producer HIDIROĞLU FLOUR MILLS taken as an example in the study gives importance to measurement, documentation and information systems management. The control mechanism is improved and the...
ŞAFİİ MEZHEBİNDE KURBAN İBADETİ VE UDHİYYENİN TAYİNLE NEZRE DÖNÜŞME MESELESİ
NİZAMETTİN ERGÜVEN
ŞAFİİ MEZHEBİNDE KURBAN İBADETİ VE UDHİYYENİN TAYİNLE NEZRE DÖNÜŞME MESELESİ
Kıyas ve Akıl Ehl-i Sünnet Usûlündeki Kıyas Delili İle Câferîler'deki Akıl Delilinin Karşılaştırılması
NİZAMETTİN EGÜVEN
Kıyas ve Akıl Ehl-i Sünnet Usûlündeki Kıyas Delili İle Câferîler'deki Akıl Delilinin Karşılaştırılması
Internet Use and Understanding the Tendency for Media Use in the Post-COVID Period
Yegen, Ceren
The COVID-19 Pandemic, which has affected the world, has also affected the manner of accessing information and news. Individuals have made extensive use of the Internet and new media technologies to obtain information and news quickly and reliably during the pandemic process. The subject of this study is how individuals can obtain information after COVID-19, and how they are affected by the Internet. For this reason, survey-based research is conducted both in Turkey and Ukraine in this study. In the process, called post-COVID, which characterizes the post-pandemic period, the current view of individuals’ Internet usage and their tendency to receive information and news is investigated.
Sustainability, Digital Security, and Cyber Hygiene During the Covid-19 Pandemic
Yegen, Ceren
The COVID-19 Pandemic has affected and transformed the world since the end of 2019. In the pandemic process, individuals, along with health concerns, also carried concerns about getting true information and news or protecting their digital footprints and cyber security. So much so that the internet is in almost every stage of life. With the pandemic, there has been a transition to sustainable practices such as online shopping, banking, trade, business, and education models. At this point, the concept of cyber hygiene, which provides digital security as well as maintaining it, is important. It is also aimed to stay away from bad and dirty content and to be prepared against cyber attacks. Therefore, cyber hygiene is in a key position in digital security. Therefore, in this study, the concept...