Synthesis of novel aminocarbo-N-thiol pyrrolidine derivatives and their antituberculosis activities
Poyraz, Samet | Nural, Yahya | Ülger, Mahmut | Belveren, Samet | Gemili, Müge | Erşen, Duygu | Serin, Mehmet Sami | Döndaş, Hacı Ali
Pyrrolidine and aminocarbothiol pyrrolidine derivatives have been extensively studied during the last decade due to possessing biological and pharmacological properties such as antifungal, antibacterial and antimalarial activity [1-3]. Pyrrolidine ring also have important place in drug research and this structure is present in many alkaloids and drug molecules [1].
Synthesis and antimycobacterial activity of Co(III) complexes of N-benzoyl-4,6-dioxo-hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carbothioamide derivatives”,
Nural, Yahya | Gemili, Muge | Ersen, Duygu | Ulger, Mahmut | Belveren, Samet | Poyraz, Samet | Serin, Mehmet Sami | Dondas, Haci Ali
S) ligands, play an impotrant role in drug research studies and it has been reported that some of Co(III) complexes show antimycobacterial, antimicrobial, antiviral and other biological activities [1]. Likewise, N-aryl/acyl thiourea derivatives have been intensivelly studied in many chemistry disciplines due to their significant complexation and biological properties [2]. One of the other important classes of drug research studies is heterocyclic compounds containing nitrogen atom as pyrrolidine and its derivatives [3].