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Yayıncı TAYLOR & FRANCIS
166490

Significance of catechol-O-methyltransferase gene polymorphism in myofacial pain syndrome

Erdal, Mehmet Emin

The objective was to investigate possible association of the catechol o-methyl transferase (COMT) gene polymorphisms with myofacial pain syndrome (MFPS). The polymorphism of the COMT gene was compared between 49 patients with MFPS and 113 control subjects. Relationship between COMT polymorphism and psychiatric status of the patients was also assessed using SCL-90-R, BDS, and STAI-I and II tests. A PCR-based restriction fragment length polymorphismassay was used to detect G ! A transition at position 1947 in COMT. There was no relationship between MFPS and COMT polymorphism (p > 0:05). The patients who had MFPS without any temporomandibular joint problem had signiŽ cantly higher expression of LL genotype when compared to those with joint problems (p < 0:05). There was no relationship betwee...

Makale2003The Pain Clinic 26 | 0 Erişime Açık
166583

Reflection of the mother–daughter relationship on the perception of birth: a qualitative study among pregnant women

Beşen, Meltem Aydın | Yurdakul, Mine

This research is conducted to examine the effect of pregnant women’s relationships with their mothers on their perception of birth. This is a qualitative analytic study. This research is carried out with 19 pregnant women who received service from a state hospital in a southern province of Turkey between November-December 2020. Pregnant women between the ages of 18–35, at the 32nd gestational week and above, and who had an active relationship with their mother were included in the study. Data were collected by interview method using semi-structured questions. Descriptive analysis was performed for the analysis of the data. All transcripts were evaluated by two researchers and codes were created. The codes formed the subthemes in terms of similarities and differences, themes were created a...

169834

Degradation of isoniazid by anodic oxidation and subcritical water oxidation methods: Application of Box–Behnken design

Gözmen, Belgin | Görmez, Özkan | Doğan Çalhan, Selda

Pharmaceutical compounds released into the aquatic environment are known to cause toxic effects on the environment. Isoniazid is widely used in the treatment of tuberculosis and is, therefore, frequently encountered in environmental waters. In this study, the degradation of isoniazid was investigated by anodic oxidation and subcritical water oxidation method which are members of Advanced Oxidation Processes. The Box–Behnken Design was used to determine the effects of current, initial concentration, and electrolysis time on mineralization in the anodic oxidation process, which carried out a cell with a Pt cathode and boron-doped diamond anode. The highest mineralization value of 78.14% was achieved at optimal conditions of 300 mA, 3 h, and 100 mg/L initial concentration. The degradation of ...

169838

Removal of imipramine using advanced oxidation processes: Degradation products and toxicity evolution

Doğan Çalhan, Selda | Görmez, Özkan | Gözmen, Belgin | Şüküroğlu, Ayça

Pharmaceuticals are frequently detected in natural and wastewater bodies, and are very important in environmental toxicology because of their stable nature. Advanced oxidation methods used to remove contaminants are of great benefit, especially removing pharmaceuticals unsuitable for biodegradation. In this study, imipramine was degraded by anodic oxidation and subcritical water oxidation, which are advanced oxidation methods. The determination of degradation products was performed by Q-TOF LC/MS analysis. The genotoxicity and cytotoxicity of the degradation samples were determined by the in vivo Allium Cepa method. Among the anodic oxidation samples, the lowest cytotoxicity was obtained after using 400 mA current, and 420 min of degradation time. No cytotoxic effect was observed in any su...

169826

Degradations of model compounds representing some phenolics in olive mill wastewater via electro‐Fenton and photoelectro‐Fenton treatments

Gözmen, Belgin

The electrochemical oxidation of vanillic acid, o‐coumaric acid and protocatechuic acid, three representative toxic phenolics in olive mill wastewater, was studied using carbon felt cathode in the electro‐Fenton system. Results obtained, in the presence or absence of UV support, were compared throughout the degradation processes up to mineralization. It was demonstrated that all three phenolic compounds reacted completely with hydroxyl radicals and degraded efficiently. It was shown in the photoelectro‐Fenton process that the degradation and mineralization efficiency of the phenolic compounds were enhanced by the effect of UV light, especially at the later stages of the degradation processes.

169840

Acid Red 1 and Acid Red 114 decolorization in H2O2-modified subcritical water: process optimization and application on a textile wastewater

Gözmen, Belgin

Solutions of Acid Red 1 and Acid Red 114 were treated in H2 O2 -modified subcritical water in the temperature range of 100°C–200°C for up to 60 min. Response surface methodology based on the Box-Behnken design was used to optimize the process. For Acid Red 1, optimum decolorization of 97% can be achieved at 192°C, 181 mM H2 O2 , 51.3 min treatment time, and 121 mg/L dye concentration. For Acid Red 114, the optimum conditions were 195°C, 157 mM H2 O2 , 38 min treatment time and 110 mg/L dye concentration, where 91% decolorization could be obtained from the proposed model. It was determined that temperature is the most important factor, followed by the oxidant concentration. Degradation was less efficient for AR114 due to the double azo bonds, compared to the single azo bond of A...

166160

A study on water quality and trophic state of Akgöl Lagoon (Mersin, Turkey).

Alp, Mehmet Tahir | Fakıoğlu, Yunus Emre | Özbay, Özgür

This study aimed to determine the physicochemical characteristics of the water quality and trophic state of Akgol Lagoon located in the eastern Mediterranean. Cluster analysis clearly revealed the € spatial heterogeneity classifying sampling stations as saline and freshwater/brackish water sites. A multivariate analysis of variance followed by principal component analysis supported that salinity was major factor affecting physicochemical water quality variations in the lagoon. As salinity was mainly governed by freshwater inflows depending on agricultural irrigation, it can be proposed that water quality was significantly influenced from freshwater use by human activities. The parameters used as predictors (total nitrogen, total phosphorus, chlorophyll a and Secchi disk transparency) yield...

169841

Degradation of nitroaromatic compounds in subcritical water: application of response surface methodology

Gözmen, Belgin | Gizir, Ahmet Murat

In this study, subcritical water has been used as a medium for degradation of 2,4-dinitrotoluene (2,4-DNT), 4-nitrotoluene (4-NT) and 2-amino-4-nitrotoluene (2-A-4-NT). The effect of temperature, oxidant concentration and time were studied and the optimal combination of reaction parameters was established using response surface methodology in a Box-Behnken design. Of all the parameters examined, temperature showed the most positive effect on the degradation of the nitroaromatic compounds. Optimal reaction conditions were found to be a temperature of 240°C, 210°C and 236°C, time of 180, 178 and 172 min, oxidant concentration of 100, 99.64 and 99.61 mM for 2,4-DNT, 4-NT and 2-A-4-NT, respectively. Since high-temperature was applied, the possibility of formation of subcritical degradat...

170022

The Optimization of the Esterification Reaction in Biodiesel Production from Trap Grease

Resitoglu, Ibrahim Aslan

In this experimental study, biodiesel production from waste oils (trap grease), which were obtained from an oil separator, was carried out by using sulfuric acid as the catalyst and esterification process. The main variables involved in the esterification process, including methanol/waste cooking oils ratio, amount of acid catalyst, reaction time, and reaction temperature, were analyzed. Because the waste cooking oils contain high free fatty acid above 65%, the esterification process has been preferred. Methanol was used as alcohol in this process because of its low cost, and sulfuric acid was preferred as the catalyst because it gives very high yields in alkyl esters. Experiments have been performed to determine optimum conditions for this esterification process in different molar ratios,...

170654

Potential renoprotective effects of silymarin against vancomycin-induced nephrotoxicity in rats

Güzel, Sevda | Uçkun, Zuhal | Canacankatan, Necmiye | Antmen, Ş. Efsun | Kibar, Deniz | Coşkun Yılmaz, Banu

Silymarin (SLY), a flavonoid complex isolated from the seeds of Silybum marianum (Asteraceae), has antioxidant, anti-apoptotic, anti-inflammatory, and anti-lipid peroxidative effects. Vancomycin (VA), used for treating serious infections, has been associated with nephrotoxicity, which limits its use. Therefore, this study aimed to investigate the potential renoprotective effects of SLY on VA-induced nephrotoxicity using renal, apoptotic (caspase-3, caspase-8, and caspase-9 enzyme activities), and oxidative stress [nitric oxide (NO) and malondialdehyde (MDA)] markers; serum blood urea nitrogen (BUN) and creatinine levels; and histopathological examination. A total of 49 male Wistar albino rats were used (n = 7): control [saline, intraperitoneally (i.p.)], dimethyl sulfoxide (i.p.), VA [400 ...

170020

The Influence of Diesel Fuel-biodiesel-ethanol-butanol Blends on the Performance and Emission Characteristics of a Diesel Engine

Resitoglu, Ibrahim Aslan | Sugözü, İlker

In this study, performance and exhaust emissions of a diesel engine fueled with Fuel A (60% diesel-30% biodiesel-5% ethanol-5% butanol) and Fuel B (40% diesel-50% biodiesel-5% ethanol-5% butanol) were investigated. The biodiesel produced from trap grease was obtained with an oil separator. Fuel A and Fuel B were tested in a single cylinder, four-stroke diesel engine at full load conditions. Compared with diesel fuel, the performance characteristics of blend fuels slightly deteriorated while the emission characteristics improved significantly. CO and HC emissions decreased by 87.01 and 87.50%, respectively.