Determination of Sample Size Using Resource Equation Methods in Analysis of Variance Models in Animal Studies

Erdoğan, Semra

The Resource Equation Method is a method developed as an alternative to power analysis for the calculation of sample size in animal studies. With this approach, the sample size is calculated based on the error degrees of freedom (DF) in the variance analysis model. In this study, one and two-factor variance analysis models, which are commonly used in animal studies, are discussed. The minimum and maximum sample size required for these models were calculating and presented in tables. While a minimum of 12 and a maximum of 21 animals in total are sufficient for two independent groups (Design 1), and the total number of animals goes up as the number of groups increases. In one factor, repeated-measures experiment design (Design 2), it was observed that the number of animals to be included in ...