Predicting driver injury severity is critical for enhancing road safety, but it is complicated because fatal accidents inherently create class imbalance within datasets. This study conducts a comparative analysis of machine-learning (ML) and deep-learning (DL) models for multi-class driver injury severity prediction using a comprehensive dataset of 107,195 traffic accidents from the Adana, Mersin, and Antalya provinces in Turkey (2018–2023). To address the significant imbalance between fatal, injury, and non-injury classes, the hybrid SMOTE-ENN algorithm was employed for data balancing. Subsequently, feature selection techniques, including Relief-F, Extra Trees, and Recursive Feature Elimination (RFE), were utilized to identify the most influential predictors. Various ML models (K-Nearest ...