Evidence‐Based Treatment Ladder for Chronic Prostatitis/Chronic Pelvic Pain

BAŞARANOĞLU,MERT | AKBAY,ERDEM

ABSTRACT Objective: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) affects 2%–10% of men worldwide, yet lacks stan dardized treatment algorithms. This study aimed to establish a definitive treatment hierarchy by comparing four therapeutic modalities: alpha‐blocker monotherapy, alpha‐blocker plus antibiotic combination, alpha‐blocker plus saw palmetto combi nation, and transurethral resection of prostate (TUR) surgery. Materials and Methods: This retrospective comparative cohort study analyzed 200 adult males with CP/CPPS (50 patients per group) treated at a single academic center between October 2023 and August 2025. Inclusion criteria comprised NIH Chronic Prostatitis Symptom Index (NIH‐CPSI) total score ≥ 10 and pain score ≥ 4, with excluded bacterial infection. Pri...