Abstract Background Large language models (LLMs) demonstrate increasing potential in healthcare applications, yet their clinical utility in specialized pediatric medicine remains inadequately characterized. This study evaluated LLM performance in pediatric urology to establish evidence-based implementation frameworks. Methods We conducted a two-phase evaluation of thirteen current-generation LLMs between January and April 2025. Phase 1 assessed clinical decision support using 180 standardized cases stratified by complexity (126 routine, 54 complex) based on European Association of Urology pediatric guidelines. Phase 2 evaluated patient education effectiveness across four common pediatric urological conditions. Performance was measured using mathematical similarity metrics and standardized ...
Abstract Purpose We aimed to compare the efficacy of three different antiseptic methods to determine the most effective prophylactic approach to prevent infectious complications after transrectal ultrasound-guided prostate biopsy (TRUS-PB). The methods evaluated were transrectal povidone-iodine injection (TRPI), biopsy needle disinfection with chlorhexidine, and biopsy needle disinfection with formalin. Methods Between January 2018 and January 2023, 904 patients who underwent TRUS-PB were retrospectively analyzed. All patients had prophylactic antibiotic use and negative urine/rectal culture results. Patients were divided into three groups according to the antiseptic protocol: Group 1 (n = 245) received only TRPI injection into the rectum before biopsy, Group 2 (n = 295) received only chlo...