Bloodstream infections caused by carbapenemresistant Klebsiella pneumoniae: analysis of risk factors, treatment responses and mortality
Bozok, Tuğçe Şimşek | Bozok, Taylan | Şahinoğlu, Mustafa Serhat | Kaya, Hamide | Horasan, Şahin Elif | Kaya, Ali
Objective: Bloodstream infections (BSIs) caused by carbapenem-resistant Klebsiella pneumoniae (CRKP) are a serious threat to public health. In this study, it was aimed to evaluate the risk factors, treatment, length of hospitalisation and mortality of patients with BSI caused by CRKP. Methods: Between October 2021 and October 2023, patients aged 18 years and older who were treated for BSI at Mersin University Faculty of Medicine Hospital and had pathogens identified as CRKP or carbapenem-sensitive Klebsiella pneumoniae (CSKP) were retrospectively reviewed and included in the study. Results: Of the 107 patients with BSI included in the study, 66 (61.7%) had CRKP and 41 (38.3%) had CSKP. The risk factors associated with CRKP in BSIs were found to be acute renal failure (p¼0.048), mech...
Ventilator-associated pneumonia due to extensive drug-resistant Acinetobacter baumannii: risk factors, clinical features, and outcomes
Ozgur, Eylem Sercan | Horasan, Şahin Elif | Ersöz, Gülden | Nayci Atış, Sibel | Kaya, Ali
Acinetobacter baumannii is characterized by a rapid development of resistance to the commonly used antimicrobial agents. We investigated the risk factors, clinical features, and outcomes in ventilatorassociated pneumonia (VAP) caused by extensive drug-resistant Acinetobacter baumannii (XDRAB). Clinical parameters and overall in-hospital mortality rates were compared between the VAP with and without XDRAB infection groups. This study showed that VAP caused by XDRAB was not associated with in-hospital mortality. However, it was related to high Simplified Acute Physiology Score II scores and increasing durations of hospital stays.