Identifıcation of Healthy Life Style Behaviors and Emotional States of Syrian Woman Refugees
Yılmaz, Mualla | Yaman, Zeliha | Temel, Gülhan
Introduction and purpose: Syrian refugee women are one of the risk groups in the field of health. The purpose of this study is to determine the healthy lifestyle behaviors and mental states of Syrian refugee women with low socio-economic status living outside the camps. Method: The universe of the descriptive study consisted of 120 Syrian refugee women enrolled in the Turkish language course at the Karacaoğlan Public Education Center in the Akdeniz district of Mersin in the spring semester of 2015-2016. The sampling method was not used, and 87 women who attended the course, were literate, could answer the questions in the data collection form, had a cognitive health level and volunteered to participate in the study. Personal Information Form, Healthy Lifestyle Behaviors Scale II and Brief ...
hsa‑miR‑17‑5p: A Possible Predictor of Ombitasvir/Paritaprevir/ Ritonavir+Dasabuvir±Ribavirin Therapy Efcacy in Hepatitis C Infection
Zehra Öksüz | Enver Üçbilek | Mehmet Sami Serin | Serkan Yaraş | Gülhan Örekici | Temel Orhan Sezgin
Although persistent sustained viral response rates are increased in hepatitis C infection following administration of direct acting antiviral (DAA) agents, the pre-use predictive parameters of these antivirals and the clinical progression in patients post-treatment remain unknown. To obtain data pertaining to the predictive parameters prior to the use of ombitavir/paritaprevir/ritonavir+dasabuvir and the clinical progression in patients following antiviral treatment. The expression profles of miR-223-3p, miR-17-5p, miR-24-3p, and TLR2 − 196 to − 174 del/ins polymorphisms from the blood/serum of 34 hepatitis C virus (HCV)-infected patients pre- and post-ombitavir/paritaprevir/ritonavir+dasabuvir treatment were determined by RT-qPCR. The expression levels of miR-17-5p (P0.05); neverthe...
Investigation of the anticancer of photodynamic therapy effects by using the novel Schiff base ligand palladium complexes on human breast cancer cell line
Demirbağ, Burcu | Ballı, Ebru | Orekici Temel, Gülhan | Yılmaz, Mustafa Kemal | Değirmenci, Evren | Kibar, Deniz
Chemotherapy plays a role in many cancer therapies, including breast cancer, but due to its significant side effects, alternate treatment approaches have been investigated. One such alternative is photodynamic therapy (PDT), which employs a combination of oxygen, a photosensitizer (PS), and light of a specific wavelength. Transition metal complexes and SBL have gained interest in PDT. In this study aimed to assess the potential antitumor activity and underlying mechanism of a newly synthesized Schiff base ligand (SBL)-mediated PDT on MCF-7 cells, comparing its efficacy to cisplatin. We synthesized and characterized two novel Pd-conjugated SBL compounds (complex-1 and 2). Following the treatment of MCF-7 cells with these compounds, a light-emitting diode (LED) was utilized to deliver a ligh...