The aim is to investigate the effect of resveratrol on micro-shear bond strength (µSBS) of adhesive to enamel after 40% hydrogen peroxide application. For µSBS test, 50 teeth were obtained, 2/3 of crowns were embedded into acrylic resin. After application of hydrogen peroxide twice, teeth were randomly allocated to control group and 9 groups (n = 15) according to concentrations (0.5, 1, 2 µM) and application periods (10, 30, 60 min) of resveratrol. Following, composite resin was placed onto enamel surfaces using 3 tygon tubes for each tooth. µSBS test was performed and failure modes were displayed. To analyze µSBS values, Kruskal Wallis and Mann-Whitney U tests were performed. µSBS values of 1 µM resveratrol for 10 min applied group were statistically higher than control group (p < 0.05). 1 µM resveratrol showed higher µSBS values than 0.5 µM and 2 µM (p < 0.05). No significant difference was detected between application periods (p > 0.05). The improvement of µSBS values with 1 µM resveratrol application may be promising for clinical problems related to reduced bond strength after bleaching.