Accumulation and Elimination of Cadmium by the Nile Tilapia (Oreochromis niloticus) in differing Temperatures and Responses of Oxidative Stress Biomarkers

FAHRİ KARAYAKAR | BEDİİ CİCİK

The aims of this study were to investigate the accumulation (15 days) and elimination (15 and 30 days) of cadmium (Cd) in the liver, gill, kidney and muscle of Oreochromis niloticus following exposures to different concentrations (1 and 2 mg/L) of Cd at different water temperatures (20, 25, 30 o C). Additionally, responses of oxidative stress biomarkers (superoxide dismutase, SOD; catalase CAT; glutathione peroxidase, GPx and malondialdehyde, MDA) of the liver were determined following Cd exposures. In accumulation period, Cd levels increased significantly in all the tissues at all temperature ...Daha fazlası

Makale 2022 Bulletin of Environmental Contamination and Toxicology109 , pp. 1 - 1134 17 Görüntülenme

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Changes in Liver Tissue Trace Element Concentrations During Hepatitis B Viral Infection Treatment

FAHRİ KARAYAKAR | TAHSİN ÇOLAK

Approximately 350–400 million people in the world have Hbs Ag (hepatitis B virus surface antigen) positivity. In the international guidelines, the permanent suppression of replication in chronic hepatitis B virus (HBV) infection therapy is reported as the primary therapeutic goal. Trace elements play a key role in liver diseases. The aim of our study is to determine some trace element concentrations in the liver during HBV treatment periods. The measurement of 11 trace elements (manganese, lead, nickel, chromium, cadmium, iron, copper, zinc, silver, cobalt, and aluminum) was carried out by the ...Daha fazlası

Makale 2019 Biological Trace Element Research188 , pp. 2 - 250 25 Görüntülenme

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Prophylactic efect of myricetin and apigenin against lipopolysaccharide‑induced acute liver injury

FAHRİ KARAYAKAR | FERBAL ÖZKAN YILMAZ | ARZU ÖZLÜER HUNT

Background Liver has an important role in the initiation and progression of multiple organ failure that occurs in sepsis. Many natural active substances can be used to reduce the liver injury caused by sepsis. For this aim, the efects of myricetin and apigenin on mice model of acute liver injury was evaluated in this study. Methods and results Thirty-six mice were randomly divided into six groups as; control, lipopolysaccharide (LPS) (5 mg/kg), LPS+myricetin (100 mg/kg), LPS+myricetin (200 mg/kg), LPS+apigenin (100 mg/kg), and LPS+apigenin (200 mg/kg) groups. Myricetin and apigenin were admini ...Daha fazlası

Makale 2021 Molecular Biology Reports48 , pp. 6 - 6373 44 Görüntülenme

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Heavy metal levels in economically important fish species sold by fishermen in Karatas (Adana / TURKEY)

FAHRİ KARAYAKAR | UMUT IŞIK | BEDİİ CİCİK

In this study, heavy metal (Cu, Zn, Cr, Cd, Pb and As) levels in the muscle of economically important fish species (Trachurus mediterraneus, Sparus aurata and Pegusa lascaris) living in different water columns in the North-East Mediterranean Sea were measured. Fish were bought from local fishermen between September 2016-August 2017 in Karatas¸ region (Adana, Turkey). Levels of Cd, Cr, Pb and As were highest in the muscle of T. mediterraneus, S. aurata and P. lascaris in the autumn season, while Cu levels were highest in T. mediterraneus and S. aurata in the spring season. The lowest and highes ...Daha fazlası

Makale 2022 Journal of Food Composition and Analysis106 ( 2022 ) , pp. 1 - 6 16 Görüntülenme

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Liver tissue trace element levels in HepB patients and the relationship of these elements with histological injury in the liver and with clinical parameters

FAHRİ KARAYAKAR | TAHSİN ÇOLAK

Aim: In this study, the relationship of liver tissue trace element concentrations with hepatitis B disease and the effects of several environmental factors were analysed. Method: The liver tissue concentrations of Al, Fe, Cd, Mn, Cr, Cu, Pb, Ni, Zn, Ag, and Co were evaluated in 92 patients with hepatitis B using the Inductively Coupled Plasma − Mass Spectrometry (ICP/MS) method in the analyses. The patients were divided into the following two groups: low-high Ishak histologic activity index (HAI) (0–6: Low Histologic Activity, 7–18: High Histologic Activity) and low-high fibrosis (FS) (Fibro ...Daha fazlası

Makale 2018 Journal of Trace Elements in Medicine and Biology45 , pp. 7 - 77 34 Görüntülenme