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The Pain Clinic3
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Ekoloji2
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Lalahan Hayvancılık Araştırma Enstitüsü Dergisi Livestock Studies2
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ANNALS OF MICROBIOLOGY1
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Annals of Microbiology1
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Bulletin of Environmental Contamination and Toxicology1
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DEPRESSION AND ANXIETY1
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ENVIRONMENTAL SCIENCE & TECHNOLOGY1
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Environmental Science & Technology1
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European Psychiatry1
Tilapia nilotica L 1758 nin Solungac ve Karaciger Dokularindaki Mangan Demir ve Cinko Duzeyleri Uzerine Bakirin Etkisi
Ahmet Erdem Dönmez, | Cafer Erkin Koyuncu
Tilapia nilotica (L., 1758) 7 ve 14 günlük sürelerle 2,0 ve 4,0 ppm bakır ortam derişimlerinde tutularak, bakırın karaciğer ve solungaç dokularındaki mangan, demir ve çinko elementleri düzeyine etkisi belirlenmiştir. Yaş yakma yöntemi ile analize hazırlanan doku örneklerinin element düzeyleri, atomik absorpsiyon spektrofotometresi yardımıyla kuru ağırlık olarak hesaplanmıştır. Bakır, solungaç dokusuna göre karaciğer dokusu element düzeyini daha fazla etkilemiştir. Ancak solungaç dokusu demir düzeyi 14. günde 4 ppm ortam derişiminde, çinko düzeyi ise 7. günde aynı ortam derişiminde istatistik ayrım gösterecek şekilde değişmiştir. Genel anlamda bakır karaciğer dokusundaki mangan, demir ve çinko elementleri düzeyinde artışa neden olmuştur.
Tardive dyskinesia is not associated with the polymorphisms of 5-HT2A receptor gene, serotonin transporter gene and catechol-o-methyltransferase gene
Erdal, Mehmet Emin
Background. – The pathophysiology of tardive dyskinesia (TD) is not completely understood. Aim. – To assess the relationship of TD with 5-HT2A receptor gene, serotonin transporter gene (5 HTT), and catechol-o-methyltransferase (COMT) gene polymorphisms. Method. – Our study comprised 111 unrelated subjects who strictly met DSM-IV criteria for schizophrenia and 32 TD, and 79 healthy unrelated controls; all the subjects were of Turkish origin. The analyses of 5-HT2A receptor gene, 5 HTT gene, and COMT gene polymorphisms were performed using polymerase chain reaction (PCR) technique. Results. – The polymorphisms of these genes were not significantly different between the schizophrenic patients, TD and control subjects. Conclusion. – Our findings indicated that 5-HT2A receptor gene, 5 HTT gene,...
Serum zinc and alkaline phosphatase values in pediatric bone marrow transplantation patients
Zinc (Zn) plays an important role in the maintenance of immune functions, including cellular/humoral immunity, and in the prevention of oxidative injury. Therefore, the maintenance of a normal Zn status may be important in bone marrow transplantation (BMT) patients. Serum Zn levels were determined in 35 children during the BMT period. In addition, as Zn-related factors, serum Cu levels and alkaline phosphatase (AP) activity were also measured. There was a significant decrease in Zn and AP values during the immediate post-transplant period (lowest at day +7) when compared to pre-BMT levels (p < .01). The patients who developed hypozincemia were more likely to be transplanted for a diagnosis of malignant disorder and were younger, and adverse events appeared to occur more frequently. This pr...
Significance of catechol-O-methyltransferase gene polymorphism in myofacial pain syndrome
Erdal, Mehmet Emin
The objective was to investigate possible association of the catechol o-methyl transferase (COMT) gene polymorphisms with myofacial pain syndrome (MFPS). The polymorphism of the COMT gene was compared between 49 patients with MFPS and 113 control subjects. Relationship between COMT polymorphism and psychiatric status of the patients was also assessed using SCL-90-R, BDS, and STAI-I and II tests. A PCR-based restriction fragment length polymorphismassay was used to detect G ! A transition at position 1947 in COMT. There was no relationship between MFPS and COMT polymorphism (p > 0:05). The patients who had MFPS without any temporomandibular joint problem had signi cantly higher expression of LL genotype when compared to those with joint problems (p < 0:05). There was no relationship betwee...