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BMC Oral Health3
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Scientific Reports3
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Mikrobiyoloji Bülteni2
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The American Journal of Emergency Medicine2
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Advances in Hematology1
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American Journal of Emergency Medicine1
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American Journal of Orthodontics and Dentofacial Orthopedics1
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Annals of Hematology1
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Applied Nursing Research1
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Archives of Oral Biology1
The osteoinductive potential of different root-end filling materials in a rat femur model
Aksu, Seckin | Kucuk, Ayse Ozcan
In pediatric dentistry, the enduring success of root-end filling materials employed for the establishment of apical plugs in immature teeth undergoing endodontic intervention is contingent upon their possessing a robust osteoinductive capacity. Hence, the primary objective of this study was to histologically assess the osteoinductive potential of four distinct dental materials, specifically recommended for retrograde filling applications, utilizing an animal hard tissue model. Within the designed experimental model, two bone defects measuring 2 mm in diameter and 2 mm in depth were created in both femurs of a cohort comprising 21 male Wistar albino rats. The first defect in the right femur was left blank as the control group, and Neo MTA Plus was placed in the second defect. The EndoSequen...
A comparative study of polishing systems on optical properties and surface roughness of additively manufactured and conventional resin based composites
ayşe tuğba ertürk avunduk | sevim atılan yavuz | hande filiz | Cengiz Yanardag, Esra
This study aimed to compare polishing systems on color stability, surface roughness, and gloss of additively manufactured permanent and conventional resin composites. Totally 250 disc specimens (6 mm*2 mm) were prepared from resin-based materials [G-ænial Posterior (GP), Clearfil Majesty Esthetic (CME), SonicFill-2 (SF), Tescera (Tes), and Crowntec (CT)]. Following baseline color (ΔE00), gloss (GU), and surface roughness (Ra) measurements, the specimens were randomly divided into 5 groups (n= 10/group) according to polishing systems: Control (mylar strips); OneGloss; OneGloss + Platina Hi-Gloss; OptiDisc; and OptiDisc + Platina Hi-Gloss. Specimens were immersed in coffee for 144 h following polishing. ΔE00, GU, and Ra measurements were repeated. Atomic force microscopy images were taken in...
Nucleated red blood cells as predictor of all-cause mortality in emergency department
Hüseyin Narcı | Cüneyt Ayrık | Mehmet Burak Yavuz Çimen
Bacground: Nucleated red blood cells (NRBCs) are immature erythrocytes that are not normally detected in the blood of healthy adults. The detection of these cells in peripheral blood is associated with increased mortality and poor prognosis. In this study, we aimed to investigate whether NRBCs predict for all causes of death in patients admitted to the emergency department (ED). Method: This study was conducted retrospectively between January 2019 and December 2019 in academic emergency department, faculty of medicine. We included all patients who died of non-traumatic causes and The control group consisted of patients discharged from the ED. NRBCs and other laboratory parameters were compared between the two groups. The primary outcome is all-cause mortality in the ED. Multivariate log...
Determining risk factors of bleeding in patients on warfarin treatment
Evren Uygungül | Cuneyt Ayrik | Huseyin Narci | Semra Erdoğan | Ibrahim Toker | Filiz Demir | Ulas Karaaslan
Background. Warfarin is a commonly used oral anticoagulant agent. The most common adverse effects of warfarin are bleeding complications. Methods. We performed a 1-year retrospective chart review of emergency department patients using warfarin. A total of 65 patients with bleeding disorder (study group) and 63 patients without bleeding (control group) were included, making up a total of 128 subjects. Demographic data, frequency of international normalized ratio (INR) checks, and routine blood results were extracted. Logistic regression analysis was used to determine which factors were most closely associated with bleeding complications. Results. Median age was 62.0 ± 14.4 and 61.9 ± 14.5 for study group and control group, respectively. Educational status and frequency of INR checks were si...
Evaluation of Dentist Preferences Among Children Aged 3–10 Years
Sahin, Meryem | Gonulal, Oyku Peker
Aim To determine children’s expectations regarding their dentist preferences, considering age and sex differences, and evaluate the results in terms of their communication with dentists. Study Design A cross-sectional study conducted at the Mersin University Pediatric Dentistry Clinic. Methods This study included 250 paediatric patients aged 3–10 years who presented to the Mersin University Pediatric Dentistry Clinic. Patients without comprehension or speech problems who were willing to participate were selected. The questionnaire consisted of 10 questions, with age-appropriate, easy-to-understand visuals created using the artificial intelligence-assisted Midjourney program. Results Children aged 3–10 years preferred a dentist of the same sex who was young, wore a white coat, g...
Detection and Molecular Analysis of Moxifloxacin MIC Values of Mycobacterium tuberculosis Strains Isolated from Clinical Specimens
Bozok, Taylan
Tüberküloz (TB), Mycobacterium tuberculosis kompleks grubuna ait mikroorganizmaların yol açtığı kronik, granülomatöz ve nekrotizan bir hastalıktır. Dünya Sağlık Örgütü’nün 2018 Global Tüberküloz Raporuna göre 2017 yılında 6.4 milyon yeni TB olgusu bildirilmiştir. Son yıllarda artan ilaç direnç problemi ve kesin tanı konulmasında halen zorluklar olması nedeniyle TB çağımızın büyük sağlık problemleri arasındaki yerini korumaktadır. Klinisyenler tarafından solunum yolu veya üriner sistem enfeksiyonlarında oral formu var olan florokinolon grubu ilaçların yoğun olarak kullanılmasının dirence yol açabileceği ve bunun da tedavi başarısızlıkları ile sonuçlanabileceği belirtilmektedir. Bu çalışmada, klinik örneklerden elde edilen M.tuberculosis izolatlarının moksifloksasin duyarlılıklarının fenotip...
Comparison of zygoma plates and infrazygomatic crest miniscrews used open bite treatment: A 3-dimensional finite element study
Arslan Çarpar, Kübra
Introduction: This study aimed to evaluate infrazygomatic crest (IZC) miniscrews, which represent a new approach to maxillary posterior tooth intrusion and extra-alveolar skeletal anchorage, using 3-dimensional f inite element stress analysis to predict the clinical usability instead of zygoma plates. Methods: Six different models were developed. The direction of the intrusion force was generated parallel to the maxillary first molar, and the posterior bite-block intrusion appliance was connected with 2 steel arches. A zygoma plate, stainless steel (SS)-IZC miniscrew, and a titanium alloy (TiA)-IZC miniscrew were used as anchorage units, and 200 g and 400 g of intrusion forces were applied. The cortical bone, spongious bone, stress values, and displacements in the anchorage unit were exami...
Investigation of EBA Digital Education Platform Used as the Medium of Distance Education in Turkey During COVID-19 Pandemic Process in Terms of Critical Thinking Skills
Gökalp, Serkan; Üredi, Lütfi
This paper focuses on investigating whether the contents of 6th grade math lesson in the digital education platform (EBA) used in distance education in Turkey during the COVID-19 pandemic period are appropriate to the critical thinking standards. The contents of the math lesson, which are in the digital education platform (EBA) in 2020-2021 academic years, constitute the population of the study. The course contents, which belong to “Data Collection” and “Data Analysis” subtopics of 6 th grade math lesson used in Turkey’s digital education platform (EBA) in 2020-2021 academic years, constitute the sample of the study. In the study, document analysis method is used. Based on the analysis conducted, it is concluded that the learning contents, which belong to “Data Collection and Evaluation” a...
The prognostic value of immature granulocyte in patients with acute pancreatitis
Serkan Karakulak | Hüseyin Narcı | Cüneyt Ayrık | Semra Erdoğan | Enver Üçbilek
Abstract Background: Acute pancreatitis is the inflammation of the pancreas. It can range from mild forms to life-threatening severe cases. There is not yet a marker that can detect severe cases in the early period. Early diagnosis and treatment of this disease has critical importance for prognosis. In this study, we aimed to investigate the percentage of immature granulocyte (IG %) in patients with acute pancreatitis in order to predict the severity of the disease and in-hospital mortality. Method: This study was carried out retrospectively in academic emergency department (ED), faculty of medicine between 01.01.2017 and 30.06.2019. The patients were divided into three groups as mild, moderate and severe. In addition, the patients were divided into two groups: those discharged from th...
The effect of virtual reality glasses on pain and patient satisfaction in arteriovenous fistula cannulation procedure
The Effect of Virtual Reality on AV Fistula Cannulation
ŞEN, Hatice | LAFCI BAKAR, Diğdem
Abstract Aims To determine the effect of virtual reality glasses intervention on pain, vital signs, and patient satisfaction of hemodialysis patients undergoing AVF catheter puncture. Design Randomized controlled study. Methods The study was conducted in 60 patients receiving dialysis treatment in the HD unit of a public hospital in Turkey. The data were collected via the “Patient Identification Form”, “Visual Analog Scale/VAS” and “Hemodynamics Variables Inspection Form”. The patients in the experiment group watched videos through the virtual reality glasses for totally 5 minutes in average, 2 minutes before the AVF cannulation process and 3 minutes during the process. No intervention was applied to the patients in the control group other than the normal nursing interventions in the...
The value of serum mean platelet volume in testicular torsion
Narci H
Objective To compare the serum mean platelet volume (MPV) in patients with testicular torsion and healthy control subjects. Methods This retrospective study compared clinical and demographic data from patients who underwent surgery for testicular torsion and healthy controls. Testicular torsion was diagnosed with a physical examination and Doppler ultrasonography. Age, leukocyte count, platelet count and MPV were recorded for all participants. Results A total of 50 patients with testicular torsion and 51 healthy control subjects were enrolled. There was no significant difference in age and platelet count between the two groups. Patients with testicular torsion had a significantly higher leukocyte count and MPV, compared with controls. According to receiver operating characteristic cur...
Epidemiological and molecular characterization of Enterobius vermicularis cases in Mersin, Turkey: An analysis based on mitochondrial DNA cox1 gene sequences
Gülbudak Harun | Tezcan Ülger Seda | Bozok Taylan | Aslan Gönül
Enterobius vermicularis is among the most common intestinal helminths, especially in children. Mitochondrial cox1 gene analyses revealed three genotypes (A, B, C). We aimed to evaluate the epidemiological characteristics and cox1 genotypes of E. vermicularis cases diagnosed at Mersin University Hospital. Between January 2017 and December 2023, 1496 samples were examined using the cellophane tape method, and 75 positives were identified. Epidemiological data were retrospectively analyzed. DNA was isolated from 30 positive samples via the phenol–chloroform method, and nested PCR products of the cox1 gene were sequenced. Phylogenetic analyses were performed using GenBank sequences. In a sample of patients with gastrointestinal signs, the positivity rate for E. vermicularis was 5 % (75/1496)...
Different Presentations of Patients with Transcobalamin II Deficiency: A Single-Center Experience from Turkey
Ünal,Selma | Karahan,Feryal | Arıkoğlu,Tuğba | Akar,Asuman | Kuyucu,Semanur
Objective: Transcobalamin II deficiency is a rare autosomal recessive disease characterized by decreased cobalamin availability, which in turn causes accumulation of homocysteine and methylmalonic acid. The presenting clinical features are failure to thrive, diarrhea, megaloblastic anemia, pancytopenia, neurologic abnormalities, and also recurrent infections due to immune abnormalities in early infancy. Materials and methods: Here, we report the clinical and laboratory features of six children with transcobalamin II deficiency who were all molecularly confirmed. Results: The patients were admitted between 1 and 7 months of age with anemia or pancytopenia. Unexpectedly, one patient had a serum vitamin B12 level lower than the normal range and another one had nonsignificantly elevated ...
Association between serum cytokine levels with pulp necrosis and apical periodontitis in sickle cell disease
Yilmaz,Melis | Aksu,Seçkin | Karahan,Feryal | Ertaş,Elif | Ünal,Selma
This study’s objective was to assess the relationship between serum cytokine levels and the occurrence of pulp necrosis (PN) and apical periodontitis (AP) in adolescents with Sickle Cell Disease (SCD). A total of 52 adolescents, including 29 individuals diagnosed with SCD, participated in the study. Serum cytokine levels including IL-1, IL-2, IL-4, IL-6, IL-1β, IL-8, IL-10, IL-17, and TNF-α were analyzed. Radiological and intraoral dental examinations were conducted on the same day. Electric pulp testing and cold tests were conducted on all intact crowned teeth to assess the presence of PN. Periapical index scores were derived from panoramic and periapical radiographs to identify teeth exhibiting AP. Statistical analyses were carried out using Student’s t-test, Chi-square test, Spearman co...
The role of immature granulocyte percentage in predicting acute chest syndrome and the severity of the vaso-occlusive crisis in sickle cell disease
Karahan,Feryal | Ünal,Selma | Bozlu, Gülçin
Background: Sickle cell disease (SCD) is an inflammatory disease that can result in both chronic and acute inflammation. Immature granulocytes (IG) are not-yet-mature white blood cells that can be easily detected in complete blood count (CBC) tests. In recent studies it has been suggested that IG may play a role in determining the prognosis of inflammatory diseases. The aim of our study was to investigate the role of IG percentage on predicting acute chest syndrome (ACS) and the severity of vaso-occlusive crisis (VOC) in patients with SCD. Methods: The study cohort consisted of 49 SCD patients admitted to the emergency department for VOC. If symptoms did not regress despite appropriate treatment including hydration and analgesia, they were hospitalized. Patients whose symptoms regressed...
Sickle Cell Disease and Psychosocial Well-Being: Comparison of Patients With Preclinical and Clinical Avascular Necrosis of the Femoral Head
Tezol,Özlem | Karahan,Feryal | Unal,Selma
Aim: Sickle cell disease (SCD) has significant adverse psychosocial impacts in childhood. Patients with SCD may be affected by avascular necrosis (AVN) and the most commonly involved site is the femoral head. We aimed to conduct a comparative investigation of the psychosocial well-being of pediatric SCD patients with preclinical and clinical femoral head AVN. Materials and Methods: Patients with homozygous SCD and healthy peers aged 7-17 years were included in this cross-sectional study. Psychosocial well-being was assessed by the Strengths and Difficulties Questionnaire (SDQ), parent version. SDQ scores were compared between the groups. Results: A total of 74 mother–child couples were enrolled in this study. The SCD with clinical AVN (stages I-IV) group consisted of 17 patients, SCD with...