Araştırmacılar Ferbal Özkan Yılmaz
Prof.Dr. Ferbal Özkan YılmazSU ÜRÜNLERİ FAKÜLTESİ SU ÜRÜNLERİ TEMEL BİLİMLERİ BÖLÜMÜ BALIKÇILIK TEMEL BİLİMLERİ ANABİLİM DALI
167472

Effects of Fenbutatin Oxide on Antioxidant System of Different Tissues in Cyprinus Carpio (L., 1758)

YILMAZ, FERBAL ÖZKAN | HUNT, ARZU ÖZLÜER | YALIN, SERAP

In this study, effects of sublethal concentrations of fenbutatin oxide on catalase (CAT) and superoxide dismutase (SOD) activities and lipid peroxidation in muscle, liver, kidney and brain tissues of Cyprinus carpio were investigated. The 96-hours LC50 value for fenbutatin oxide was determined as 1.544 mg/L for C. carpio in this study. 0.15 mg/L (1/10 of LC50) and 0.30 mg/L (1/5 of LC50) sublethal concentrations were applied for 96 h (4 days) in this experiment. The CAT activities in tissues were increased relation to doses applied. The SOD activities were decreased by 0.30 mg/L. The tissue MDA levels were significantly increased in relation to dose applied.

167483

The effects of freshwater rearing on the whole body and muscle tissue fatty acid profile of the European sea bass (Dicentrarchus labrax)

HUNT, ARZU ÖZLÜER | YILMAZ, FERBAL ÖZKAN | ENGİN, KENAN

The purpose of this study was to investigate the effect of freshwater rearing on the fatty acid profiles of the whole body and muscle tissue of the European sea bass (Dicentrarchus labrax). Half of initial fish were gradually acclimated to freshwater (FW) kept at the same temperature to salt water and grown in same conditions as their counterparts in saltwater (SW). The decrease in salinity caused an increase in the percentages of 18:1n − 9, 24:1n − 9, 18:3n − 3, 18:2n − 6 and decrease in the percentages of 14:0, 15:0, 20:0, 21:0, 20:5n − 3 and 22:6n − 3 both in the whole body and in the muscle tissue fatty acid profiles. The lipids of FW-reared fish contained significantly (P < 0.01) higher percentages of 18:2n − 6 and 18:3n − 6 than that of SW-reared fish. However, percentages of 20:5n −...

Makale2011Aquaculture International 19 | 0 Erişime Açık
167438

The protective role of ferulic acid against imidacloprid-induced oxidative stress in liver and brain of Cyprinus carpio

YILMAZ, FERBAL ÖZKAN | HUNT, ARZU ÖZLÜER

This study evaluated the potential protective effect of ferulic acid (FA) on stress induced by imidacloprid (IM) in Cyprinus carpio (mean weight 60.10±2.22 g). Therefore, C. carpio was exposed to sublethal IM concentration (2.80 mg/L) for 10 days. During the experimental period, fish were fed a basal (control) diet and a basal diet supplemented with 5 g/kg of ferulic acid. The fish were divided into four groups (n = 6 in each group). The control group was exposed to tap water (the absence of imidacloprid) fed with control diet. The FA group was exposed to tap water (the absence of IM) and was fed with FA supplemented diet. The liver and brain tissues of both control and treated fish were dissected. Tissues samples were obtained from an individual fish and prepared for analysis. The variat...

167453

Prophylactic efect of myricetin and apigenin against lipopolysaccharide‑induced acute liver injury

KARAYAKAR, FAHRİ | YILMAZ, FERBAL ÖZKAN | HUNT, ARZU ÖZLÜER

Background: Liver has an important role in the initiation and progression of multiple organ failure that occurs in sepsis. Many natural active substances can be used to reduce the liver injury caused by sepsis. For this aim, the efects of myricetin and apigenin on mice model of acute liver injury was evaluated in this study. Methods and results: Thirty-six mice were randomly divided into six groups as; control, lipopolysaccharide (LPS) (5 mg/kg), LPS+myricetin (100 mg/kg), LPS+myricetin (200 mg/kg), LPS+apigenin (100 mg/kg), and LPS+apigenin (200 mg/kg) groups. Myricetin and apigenin were administered orally for 7 days, and LPS was administered intraperitoneally only on the 7th day of the study. 24 h after LPS application, all animals were sacrifced and serum biochemical parameters, hist...

Makale2021Molecular Biology Reports 21 | 0 Erişime Açık
167452

Biochemical and Antimicrobial Properties of Alburnus tarichi Roe Protein Hydrolysate

YILMAZ, FERBAL ÖZKAN | HUNT, ARZU ÖZLÜER | YALIN, SERAP

The protein hydrolysates with antioxidant and antimicrobial potential have become a theme of great interest for pharmaceutical, nutraceuticals, as well as food processing and preservation industries. On the other hand, chemical composition of fish protein hydrolysates is significant in nutrition perspective of human health. Hence, in the present study proximate and amino acid compositions, antioxidant and antimicrobial activities of Alburnus tarichi roe protein hydrolysate was estimated. Protein, lipid, moisture, and ash content were found to be 87.24±0.1, 0.72±0.04, 8.79±0.3, and 7.01±0.09%, respectively. Glutamic acid, aspartic acid, lysine, leucine and alanine were found to be the most dominant amino acids, whereas, cysteine was found to be the lowest amino acid in roe protein hydrolys...

167480

Effects of dietary selenium of organic form against lead toxicity on the antioxidant system in Cyprinus carpio

YILMAZ, FERBAL ÖZKAN | HUNT, ARZU ÖZLÜER | YALIN, SERAP

In this study was evaluated potential protective effect of organic selenium (Se) on heavy metal stress induced by lead (Pb) in Cyprinus carpio. For this reason, C. carpio was exposed to sublethal concentration of Pb (1.5 mg/L Pb(NO3)2) for 14 days. The fish were fed a basal (control; measured 0.55 mg/kg Se) diet or a basal diet supplemented with 2.50 mg/kg (measured 2.92 mg/kg Se) organic Se (Sel-Plex®) during the experiment period. The variations in glutathione peroxidase (GSH-Px), glutathione S-transferase (GST) activities, and levels of reduced glutathione (GSH) with malondialdehyde (MDA) in liver and brain tissues of C. carpio were investigated in experimental groups. GSH levels in liver and brain tissues were significantly decreased by exposure to Pb. GST activity was significantly in...

167477

The protective role of ascorbic acid (vitamin C) against chlorpyrifos-induced oxidative stress in Oreochromis niloticus

YILMAZ, FERBAL ÖZKAN | HUNT, ARZU ÖZLÜER | YALIN SERAP

Ability of ascorbic acid (vitamin C) to attenuate oxidative damage was evaluated in liver and brain tissues of Oreochromis niloticus (O. niloticus) experimentally exposed to sublethal concentrations of chlorpyrifos (CPF). O. niloticus was exposed to sublethal concentrations of CPF at 12 μg/L (CPF1) and 24 μg/L (CPF2) for 96 h. The fish of vitamin C (Vit C) and CPF2 + Vit C groups were fed with Vit C supplemented diet (200 mg Vit C/100 g feed). A significant increase in thiobarbituric acid-reactive substances (TBARS) level (P < 0.05) was observed in brain of CPF-exposed fish although liver TBARS level was not changed compared to control group. This result showed that lipid peroxidation (LPO) was elevated in brain of fish exposed to CPF. Glutathione peroxidase (GSH-Px) activity in liver and ...

167471

Investigation of Glutathion S-Transferase, Adenosine deaminase, Paraoxonase Activities in Liver of Oncorhynchus mykiss Fed with Nucleotide-Yeast Supplemented Diet

YILMAZ, FERBAL ÖZKAN | HUNT, ARZU ÖZLÜER

In this study, it was evaluated Glutathione S transferase (GST), Adenosine deaminase (ADA), and paraoxonase (PON) activities in liver tissue of Oncorhynchus mykiss fed with nucleotide yeast base protein supplemented diet. Throughout the 60-day period the control group was fed a fish meal based basal diet, and three other groups were fed diets in which 20% (NP 20), 40% (NP 40) and 60% (NP 60) fish meal was substituted with nucleotide (Nu-Pro® (NP) yeast). At the end of experiment, liver tissue GST, PON and ADA activity was increased significantly (P

167467

Protective Effect of Humic Substances Against Oxidative Stress Caused by Lead in Liver of Nile Tilapia, Oreochromis niloticus (Linnaeus, 1758)

YILMAZ, FERBAL ÖZKAN | HUNT, ARZU ÖZLÜER | YALIN, SERAP

In this study, the protective effect of humic substance in the fish feed was investigated against the effects of subletal lead (Pb) concentration on the antioxidant enzyme system in Oreochromis niloticus. For this purpose, the fish which were affected by 1.5 mg/L lead nitrate Pb(NO3)2 medium concentration were fed with feed containing 0.2% of humic substance. Liver samples were taken at 4th and 10th days in this study, which included control group, humic substance (HM), Pb, and Pb + HM groups. The enzyme activity of liver tissue catalase (CAT) and superoxide dismutase (SOD) of O. niloticus and the level of malondialdehyde (MDA), a product of lipid peroxidation, increased significantly at 4th and 10th days in the group with subletal lead concentration compared with the control group. Compar...

166254

Effects of Dietary Nucleotide Yeast on Immune Responses and Antioxidant Enzyme Activities of Rainbow Trout Juveniles (Oncorhynchus mykiss)

HUNT, ARZU ÖZLÜER | YILMAZ, FERBAL ÖZKAN | ENGİN, KENAN | YALIN, SERAP

This study aimed at demonstrating the effects of dietary supplementation of nucleotide yeast base protein (Nu-Pro®) (NP) on the antioxidant enzyme activities and immune response in liver and blood tissues of rainbow trout (Oncorhynchus mykiss). Fish with an average initial weight of 27.75±0.26 g were randomly assigned to four groups with three replicates. Throughout the 60 day grow-out period the control group was fed a fish meal based basal diet, and three other groups were fed diets in which 20 (NP 20), 40 (NP 40) and 60 % (NP 60) fish meal was substituted with nucleotide (Nu-Pro® (NP) yeast). There were no significant changes of superoxide dismutase (SOD) and catalase (CAT) activities in liver among the experimental groups. A significant decrease (P

167475

Organik ve İnorganik Selenyum Katkılı Yemlerle Beslenen Oreochromis niloticus ‘da Antioksidan ve İmmün Sistem Parametrelerinin Araştırılması

HUNT, ARZU ÖZLÜER | YILMAZ, FERBAL ÖZKAN | DELİOĞLAN, ŞANSER

Bu çalışmada organik (Sel-Plex®-2000, Alltech, USA) ve inorganik selenyum (Na2SeO3.5H2O -Sodyum selenite pentahydrate-FLUCA) ilaveli yem ile beslenen Oreochromis niloticus’un karaciğer antioksidan enzim aktiviteleri ve immünsistem parametreleri araştırılmıştır. Ortalama ağırlıkları 12,62 ± 0,11 g olan balıklar, 5 farklı uygulama grubu (Kontrol; Org1,5; Org3,0; İnorg1,5; İnorg3,0) olacak şekilde akvaryumlara yerleştirilmiş ve 75 gün beslenmişlerdir. Deneme süresi sonunda karaciğer katalaz (CAT), süperoksit dismutaz (SDO), glutatyon peroksidaz (GSH-Px), lizozim (LYZ) ve miyeloperoksidaz (MPO) aktiviteleri ile malondialdehit (MDA) düzeyi ve kas selenyum seviyeleri belirlenmiştir. Karaciğer antioksidan enzim aktiviteleri ve immünsistem parametreleri Se gruplarında kontrol grubuna oranla artmış...

167476

Su Ürünleri Yetiştiriciliğinde Prebiyotikler ve Önemi

HUNT, ARZU ÖZLÜER | YILMAZ, FERBAL ÖZKAN

Dünya yetiştiricilik sektörü son yıllarda hızla büyümektedir. Artan üretim miktarına bağlı olarak yetiştiricilik yöntemleri ve yetiştiricilik teknikleri de gelişmektedir. Yetiştiricilik de kullanılan metotların gelişmesiyle birlikte su kirliliği artmakta, balıklarda stres oluşmakta, yem kalitesi azalmakta ve su içerisinde bulunan bakteri, parazit ve virüslerin hastalık etkisi çoğalmakta ve büyümeyi baskılamaktadır. Bu yüzden son yıllarda balık sağlığını iyileştirmek amacıyla prebiyotik gibi alternatif maddelerin kullanımı yaygınlaşmaktadır. Prebiyotik madde, sindirilemeyen besin içerikleridir ve vücuda alındığında yararlı bazı bakterilerin kolon içerisinde gelişimini teşvik eder. Bu derlemede, bazı prebiyotiklerin potansiyel etkileri ve yetiştiricilik açısından önemi vurgulanmıştır...

167481

Apparent Nutrient Digestibility of Balanced Diets with Soy Bean Extract or Meat and Bone Meal in the Nile Tilapia (Oreochromis niloticus L.) Infected with Vibrio anguillarum

ENGİN, KENAN | YILMAZ, FERBAL ÖZKAN

Nile tilapia, Oreochromis niloticus L., infected with Vibrio anguillarum or not infected were fed balanced diets containing vegetal (solvent extracted soy bean meal (SBM)) or animal (meat and bone meal (MBM)) protein sources in order to demonstrate the apparent nutrient and energy digestibility. Regardless of protein sources in the diets, feed intake was lower in the infected group. Apparent nutrient (AD_{DM} and AD_{CP}) and energy digestibility (AD_{kJ}) values of Nile tilapia fed the SBM diet were significantly better (P < 0.05) than those fed the CONT and MBM diets and changed little between the measurement days in both groups (non-infected and infected). Although no visible symptoms associated with vibriosis were evident on either the skin or internal organs, the significantly lower (...

167436

Mersin İli Taşucu Limanı’ndan Örneklenen Sintine SularınınKirlilik Açısından Değerlendirilmesi

YILMAZ, FERBAL ÖZKAN | HUNT, ARZU ÖZLÜER

Deniz yolu ile yapılan taşımacılığın artması sonucu, gemilerin oluşturduğu deniz kirliliği problemi, son yıllarda oldukça önem kazanmıştır. Bu çalışmada, gemi sintine sularının deniz kirliliği yönünden değerlendirilmesi amaçlanmıştır. Mersin Taşucu Limanı’nda bulunan iki farklı gemiye ait sintine suyu örnekleri alınarak pH, renk, toplam azot, toplam fosfor, askıda katı madde (AKM), hidrokarbon yağ indeksi (HYİ), kimyasal oksijen ihtiyacı (KOİ), biyolojik oksijen ihtiyacı (BOİ), yüzey aktif madde analizleri yapılmıştır. Elde edilen sonuçlar, Su Kirliliği Kontrol Yönetmeliği’nde belirtilen değerler ile karşılaştırılmıştır. Gemi 1 ve Gemi 2 ‘den alınan Sintine suyu örneklerinin analiz değerleri sırasıyla AKM 472 mg/L-1812 mg/L; HYİ 110,6-138,8 mg/L; KOİ 8870,4-17369,6 mg/L; BOİ 1606,4 -3881,1...

166296

The effects of fish meal replacement by yeast based nucleotides on growth body composition and digestive enzyme activity in rainbow trout juveniles Oncorhynchus mykiss

HUNT, ARZU ÖZLÜER | YILMAZ, FERBAL ÖZKAN | ENGİN, KENAN | YALIN, SERAP | ŞAHİN, NEFİSE ÖZLEN

This 60 day study investigated the effects of organically certified nucleotide yeast-derived protein source (Nu-Pro®) on growth, feed efficiency, fillet proximate composition and digestive enzymes in rainbow trout (Onchorhyncus mykiss). Diets were isonitrogenous and isocaloric. Three experimental diets wherein 20%, 40% and 60% of the fish meal content was replaced by Nu-Pro®, were compared to the control diet in which the crude protein content was anchovy fish meal and corn gluten meal. The rainbow trout (initial weight 27 g/fish) were fed twice daily in 200-l Aqaria. Live weight gain increase ranged from 125-195% in fish fed the experimental diets. Results indicated that up to 40% fish meal protein can be replaced by Nu-Pro® without compromising growth rates, feed efficiency or the fillet...

167486

Effects of Organic Selenium on Growth, Muscle Composition, and Antioxidant System in Rainbow Trout

HUNT, ARZU ÖZLÜER | YILMAZ, FERBAL ÖZKAN | YALIN, SERAP

This experiment was conducted to understand the effects of organic selenium on rainbow trout, Oncorhynchus mykiss. Fish (33.47±0.15 g; n = 216) were randomly assigned to four treatment groups consisting of three replicates of 18 fish each in 100 x 100 x 125 cm cages. The fish were fed a basal diet supplemented with 2, 3, or 4 mg/kg organic Se (Sel-Plex®) supplementation for 8 weeks. Muscle of fish fed the unsupplemented control diet had a lower (p

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